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Tramadol extended-release is used to treat moderate to severe chronic pain when treatment is needed around the clock. Tramadol may also be used for other purposes not listed in this medication guide. You should not take tramadol if you have ever been addicted to drugs or alcohol. Seizures (convulsions) have occurred in some people taking tramadol. You may be more likely to have a seizure while taking tramadol if you have a history of seizures or head injury, a metabolic disorder, or if you are taking certain medicines such as antidepressants, muscle relaxers, or medicine for nausea and vomiting. Take tramadol exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor. Do not take more than 300 milligrams of tramadol in one day.

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